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Verseon International Corporation is a clinical-stage pharmaceutical company based in Fremont, California. It is developing several drug discovery programs in cardiometabolic diseases and cancer featuring drug candidates that represent novel chemical matter designed using molecular physics and artificial intelligence.
High-throughput screening (HTS) is a method for scientific discovery especially used in drug discovery and relevant to the fields of biology, materials science [1] and chemistry. [ 2 ] [ 3 ] Using robotics , data processing/control software, liquid handling devices, and sensitive detectors, high-throughput screening allows a researcher to ...
Additionally, the institute specializes in stem cell research and the development of drug discovery technologies. Based in La Jolla, California, the institute employs over 500 scientists and staff. It is recognized for its NCI-designated Cancer Center, the Conrad Prebys Center for Chemical Genomics, and the Sanford Children's Health Research ...
In high-throughput screening (HTS), one of the major goals is to select compounds (including small molecules, siRNAs, shRNA, genes, et al.) with a desired size of inhibition or activation effects. A compound with a desired size of effects in an HTS screen is called a hit.
Through its programs, the ADDF has invested close to $65 million to fund nearly 450 Alzheimer's drug discovery programs and clinical trials in academic centers and biotechnology companies in 18 countries. [14] From 2000 to 2004, the ADDF provided seed funding for Amyvid, [15] the first FDA-approved diagnostic test for Alzheimer's disease.
Another method for drug discovery is de novo drug design, in which a prediction is made of the sorts of chemicals that might (e.g.) fit into an active site of the target enzyme. For example, virtual screening and computer-aided drug design are often used to identify new chemical moieties that may interact with a target protein.
Before the caps, "there were a lot of people who were facing really high out-of-pocket costs, sometimes $10,000 (or more) per year," said Leigh Purvis, prescription drug policy principal at AARP ...
Their current service areas include: High Throughput Screening (HTS), [8] Chemistry, Oncology, Infectious Disease, Neuroscience, and the Center for Neuromolecular Research. Southern Research is a founding member of the Alabama Drug Discovery Alliance (ADDA) along with the University of Alabama at Birmingham School of Medicine (SOM). The UAB ...