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Hepatitis B virus is classified in the genus Orthohepadnavirus, which contains 11 other species. [3] The genus is classified as part of the Hepadnaviridae family, which contains four other genera, Avihepadnavirus, Herpetohepadnavirus, Metahepadnavirus and Parahepadnavirus. [3] This family of viruses is the only member of the viral order ...
820,000 resulting from hepatitis B (2019) [1] Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver; [1][6] it is a type of viral hepatitis. [7] It can cause both acute and chronic infection. [1] Many people have no symptoms during an initial infection. For others, symptoms may appear 30 to 180 days ...
Infectious diseases, gastroenterology. Viral hepatitis is liver inflammation due to a viral infection. [1][2] It may present in acute form as a recent infection with relatively rapid onset, or in chronic form, typically progressing from a long-lasting asymptomatic condition up to a decompensated hepatic disease and hepatocellular carcinoma (HCC).
Virulence factors (preferably known as pathogenicity factors or effectors in botany) are cellular structures, molecules and regulatory systems that enable microbial pathogens (bacteria, viruses, fungi, and protozoa) to achieve the following: [1][2] Specific pathogens possess a wide array of virulence factors. Some are chromosomally encoded and ...
Pathogenesis is a qualitative description of the process by which an initial infection causes disease. [2] Viral disease is the sum of the effects of viral replication on the host and the host's subsequent immune response against the virus. [3] Viruses are able to initiate infection, disperse throughout the body, and replicate due to specific ...
HBeAg is a hepatitis B viral protein, produced by the HBcAg reading frame. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious). HBeAg is considered a marker for cccDNA replication. [1]
HBcAg is an antigen that can be found on the surface of the nucleocapsid core (the inner most layer of the hepatitis B virus). While both HBcAg and HBeAg are made from the same open reading frame, HBcAg is not secreted as a monomer. [3] HBcAg is considered "particulate" and it does not circulate in the blood, but recent study show it can be ...
Molecular Koch's postulates. Molecular Koch's postulates are a set of experimental criteria that must be satisfied to show that a gene found in a pathogenic microorganism encodes a product that contributes to the disease caused by the pathogen. Genes that satisfy molecular Koch's postulates are often referred to as virulence factors.