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Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
Azithromycin: Zithromax, ... Can be given to children less than 40 kilograms in weight; for children heavier, the dosage is same as adults, twice daily. ...
Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...
Azithromycin, sold under the brand names Zithromax (in oral form) and Azasite (as an eye drop), is an antibiotic medication used for the treatment of several bacterial infections. [10] This includes middle ear infections , strep throat , pneumonia , traveler's diarrhea , and certain other intestinal infections . [ 10 ]
Azithromycin stands apart from other macrolide antibiotics because it is a weak inhibitor of CYP3A4, and does not significantly increase AUC value of co-administered drugs. [ 32 ] The difference in CYP3A4 inhibition by macrolides has clinical implications, for example, for patients who take statins , which are cholesterol-lowering drugs that ...
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It contains a wide range of information and advice on prescribing for children - from newborn to adolescence. The entries are classified by group of drug, giving cautions for use, side effects, indications and dose for most of the drugs available for children in the UK National Health Service. It also includes information on the unlicensed uses ...
The selection and use of essential medicines: report of the WHO Expert Committee, 2017 (including the 20th WHO Model List of Essential Medicines and the 6th Model List of Essential Medicines for Children). Geneva: World Health Organization. hdl: 10665/259481. ISBN 978-92-4-121015-7. ISSN 0512-3054. WHO technical report series; no. 1006.