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Tricuspid regurgitation (TR), also called tricuspid insufficiency, is a type of valvular heart disease in which the tricuspid valve of the heart, located between the right atrium and right ventricle, does not close completely when the right ventricle contracts .
Moderate or severe tricuspid regurgitation is usually associated with tricuspid valve leaflet abnormalities and/or possibly annular dilation and is usually pathologic which can lead to irreversible damage of cardiac muscle and worse outcomes due to chronic prolonged right ventricular volume overload. [1]
The tricuspid valve, or right atrioventricular valve, is on the right dorsal side of the mammalian heart, at the superior portion of the right ventricle.The function of the valve is to allow blood to flow from the right atrium to the right ventricle during diastole, and to close to prevent backflow (regurgitation) from the right ventricle into the right atrium during right ventricular ...
Tricuspid regurgitation is usually secondary to right ventricular dilation [16] which may be due to left ventricular failure (the most common cause), right ventricular infarction, inferior myocardial infarction, [16] or cor pulmonale [16] Other causes of tricuspid regurgitation include carcinoid syndrome and myxomatous degeneration. [16]
Since the main causes of right ventricular hypertrophy is tricuspid regurgitation or pulmonary hypertension (discussed above), management involves treatment of these conditions. [3] Tricuspid regurgitation is typically treated conservatively by aiming to treat the underlying cause and following up the patient regularly. [12]
Tricuspid regurgitation Carvallo's sign is a clinical sign found in patients with tricuspid regurgitation . The pansystolic murmur found in this condition becomes louder during inspiration ; this sign enables it to be distinguished from mitral regurgitation .
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