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Metaphase (from Ancient Greek μετα- beyond, above, transcending and from Ancient Greek φάσις (phásis) 'appearance') is a stage of mitosis in the eukaryotic cell cycle in which chromosomes are at their second-most condensed and coiled stage (they are at their most condensed in anaphase). [1]
This is an accepted version of this page This is the latest accepted revision, reviewed on 19 December 2024. Process in which chromosomes are replicated and separated into two new identical nuclei For the type of cell division in sexually reproducing organisms used to produce gametes, see Meiosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
This interval includes the G 2 phase and metaphase (annotated as "Meta."). Further information: Karyotype G 2 phase , Gap 2 phase , or Growth 2 phase , is the third subphase of interphase in the cell cycle directly preceding mitosis .
The spindle checkpoint, also known as the metaphase-to-anaphase transition, the spindle assembly checkpoint (SAC), the metaphase checkpoint, or the mitotic checkpoint, is a cell cycle checkpoint during metaphase of mitosis or meiosis that prevents the separation of the duplicated chromosomes until each chromosome is properly attached to the ...
The metaphase checkpoint is a fairly minor checkpoint, in that once a cell is in metaphase, it has committed to undergoing mitosis. However that's not to say it isn't important. In this checkpoint, the cell checks to ensure that the spindle has formed and that all of the chromosomes are aligned at the spindle equator before anaphase begins. [49]
There are many checkpoints in the cell cycle, [1] but the three major ones are: the G1 checkpoint, also known as the Start or restriction checkpoint or Major Checkpoint; the G2/M checkpoint; and the metaphase-to-anaphase transition, also known as the spindle checkpoint. [2]
This makes us embarrassingly smell-deficient amateurs, but this is exactly why we rely so heavily on dogs to detect drugs, explosives, and even illnesses like cancer, diabetes, or infectious diseases.
Cell division plays an important role in determining the fate of the cell. This is due to there being the possibility of an asymmetric division. This as a result leads to cytokinesis producing unequal daughter cells containing completely different amounts or concentrations of fate-determining molecules.