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The treatment for mediastinal nonseminomatous germ cell tumors should follow guidelines for poor-prognosis testicular cancer. Initial treatment with four courses of bleomycin, etoposide, and cisplatin, followed by surgical resection of any residual disease, is considered standard therapy.
Treatment of testicular cancer is one of the success stories of modern medicine, with sustained response to treatment in more than 90% of cases, regardless of stage. [53] In 2011 overall cure rates of more than 95% were reported, and 80% for metastatic disease—the best response by any solid tumor, with improved survival being attributed ...
PT-DLBCL is by far the most common form of testicular cancer in men >60 years of age. [2] It usually develops in this age group (median age ~65 years old, range 10–96 years) and presents as a painless testicular mass or swelling in one testis or, in ~6% of cases, both testes: [1] PT-DLBCL is the most common testicular cancer to present with disease in both testicles. [8]
Second-line treatment is the same as for nonseminomas. [12] Stage 3 seminoma is characterized by the presence of metastasis outside the retroperitoneum—the lungs in "good risk" cases or elsewhere in "intermediate risk" cases. This is treated with combination chemotherapy. Second-line treatment follows nonseminoma protocols. [12]
This treatment option is an alternative to remove testicular cancer masses which are <20 mm, have a high probability of being benign, and with negative serum tumor markers. Its benefits include preserving fertility and normal hormone function. [7] About half of testicular cancer germ cell tumors are seminomas. Individuals with seminomas are 80 ...
This treatment uses synthetic testosterone to increase circulating testosterone levels and reduce low T symptoms. TRT comes in several forms, including skin patches, topical gels, oral capsules ...