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When the plaque does not cause symptoms, people are still at higher risk of stroke than the general population, but not as high as people with symptomatic stenosis. The incidence of stroke, including fatal stroke, is 1–2% per year. The surgical mortality of endarterectomy ranges from 1–2% to as much as 10%.
The goal of treatment is to prevent the development of an actual stroke or limit the continuation of neurologic deficits should a stroke occur after dissection. Treatments include observation, anti-platelet agents, anticoagulation, stent implantation, carotid endarterectomy, and carotid artery ligation. [10] [32]
Carotid endarterectomy itself can cause strokes, so to be of benefit in preventing strokes over time, the risks for combined 30-day mortality and stroke risk following surgery should be < 3% for asymptomatic people and ≤ 6% for symptomatic people. [1] The carotid artery is the large vertical artery in red.
The risk-reduction from intervention for carotid stenosis (stenting or endarterectomy) is greatest when the indication for intervention is symptoms (i.e., the patient is symptomatic) - typically stroke or TIA. [6] A new generation of double-layer stents is currently being developed to reduce the risk of stroke during or after the procedure.
Cervical artery dissection has been noted to be a common cause of young adult strokes, with some sources indicating a prevalence of up to 20% in this young adult population with annual incidence rates between 2.6 and 2.9 per 100,000, although these incidences may be misleading with true incidences being higher because clinical presentations can vary, many being minor or self-limited, and thus ...
The most common cause of arterial stenosis is atherosclerosis, however other pathologies such as fibromuscular dysplasia, dissection, trauma or external compression may occur. [2] Atherosclerotic plaque can rupture, resulting in a source of emboli. These emboli can cause TIAs or strokes in the areas of the brain supplied by the affected artery.
The number of people who die from stroke worldwide will jump 50% by 2050 if no significant action is taken to limit the prevalence of stroke and its risk factors, according to a new report from ...
A head and neck CT angiogram can be performed within 6 hours of onset of symptoms to see where the occlusion may be located which can help in determining the cause of the stroke. [29] In people who die from a stroke an autopsy can reveal additional diseases or conditions beyond the stroke itself, as well as uncover uncommon causes of a stroke. [30]