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  2. United Kingdom Model for End-Stage Liver Disease - Wikipedia

    en.wikipedia.org/wiki/United_Kingdom_Model_for...

    The UKELD score is calculated from the patient's INR, serum creatinine, serum bilirubin and serum sodium, according to the formula: [3] ( 5.395 × ln ⁡ I N R ) + ( 1.485 × ln ⁡ c r e a t i n i n e ) + ( 3.13 × ln ⁡ b i l i r u b i n ) − ( 81.565 × ln ⁡ N a ) + 435 {\displaystyle (5.395\times \ln INR)+(1.485\times \ln creatinine)+(3 ...

  3. Model for End-Stage Liver Disease - Wikipedia

    en.wikipedia.org/wiki/Model_for_End-Stage_Liver...

    The Model for End-Stage Liver Disease, or MELD, is a scoring system for assessing the severity of chronic liver disease.It was initially developed to predict mortality within three months of surgery in patients who had undergone a transjugular intrahepatic portosystemic shunt (TIPS) procedure, [1] and was subsequently found to be useful in determining prognosis and prioritizing for receipt of ...

  4. Assessment of kidney function - Wikipedia

    en.wikipedia.org/wiki/Assessment_of_kidney_function

    Creatinine clearance exceeds GFR due to creatinine secretion, [4] which can be blocked by cimetidine. Both GFR and C Cr may be accurately calculated by comparative measurements of substances in the blood and urine, or estimated by formulas using just a blood test result ( eGFR and eC Cr ) The results of these tests are used to assess the ...

  5. Creatinine - Wikipedia

    en.wikipedia.org/wiki/Creatinine

    Diagnostic serum creatinine studies are used to determine renal function. [4] The reference interval is 0.6–1.3 mg/dL (53–115 μmol/L). [4] It is simple to measure serum creatinine, and it is the most commonly used indicator of renal function. [6]

  6. Hepatorenal syndrome - Wikipedia

    en.wikipedia.org/wiki/Hepatorenal_syndrome

    It is defined by an increase in serum creatinine level to >133 μmol/L (1.5 mg/dL) or a creatinine clearance of less than 40 mL/min, and a urine sodium < 10 μmol/L. [7] It also carries a poor outlook, with a median survival of approximately six months unless the affected individual undergoes liver transplantation.

  7. Diabetic nephropathy - Wikipedia

    en.wikipedia.org/wiki/Diabetic_nephropathy

    To clinically stage the degree of damage in this (and any) kidney disease, the serum creatinine is determined and used to calculate the estimated glomerular filtration rate . Normal eGFR is equal to or greater than 90ml/min/1.73 m 2. [34] On biopsy, the following classification has been suggested by Tervaert et al.: [35]

  8. Chronic kidney disease - Wikipedia

    en.wikipedia.org/wiki/Chronic_kidney_disease

    The GFR is derived from the serum creatinine and is proportional to 1/creatinine, i.e. it is a reciprocal relationship; the higher the creatinine, the lower the GFR. It reflects one aspect of kidney function, how efficiently the glomeruli – the filtering units – work. The normal GFR is 90–120 ml/min.

  9. Urea-to-creatinine ratio - Wikipedia

    en.wikipedia.org/wiki/Urea-to-creatinine_ratio

    The normal serum creatinine (sCr) varies with the subject's body muscle mass and with the technique used to measure it. For the adult male, the normal range is 0.6 to 1.2 mg/dl, or 53 to 106 μmol/L by the kinetic or enzymatic method, and 0.8 to 1.5 mg/dl, or 70 to 133 μmol/L by the older manual Jaffé reaction.