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Hyoscyamine (also known as daturine or duboisine) is a naturally occurring tropane alkaloid and plant toxin. It is a secondary metabolite found in certain plants of the family Solanaceae , including henbane , mandrake , angel's trumpets , jimsonweed , the sorcerers' tree , and Atropa belladonna (deadly nightshade).
Scopolamine has been used to model the defects in cholinergic function for models of Alzheimer's, dementia, fragile X syndrome, and Down syndrome. [ 76 ] [ 81 ] [ 82 ] [ 83 ] Scopolamine has been identified as a psychoplastogen , which refers to a compound capable of promoting rapid and sustained neuroplasticity in a single dose. [ 84 ]
Hyoscine butylbromide, also known as scopolamine butylbromide [4] and sold under the brandname Buscopan among others, [5] is an anticholinergic medication used to treat abdominal pain, esophageal spasms, bladder spasms, biliary colic, [6] and renal colic. [7] [8] It is also used to improve excessive respiratory secretions at the end of life. [9]
The researchers examined medical records from 2004 through 2011 from more than 73,000 patients age 75 and older, mostly women. ... which may increase dementia risk, Kuller wrote. The drugs do ...
Some drugs used to treat type 2 diabetes could also help lower a person’s risk of neurodegenerative diseases, such as Alzheimer’s. Image credit: martin-dm/Getty Images.
A woman diagnosed with chronic dementia, 1896. Despite the fully legal status of several common deliriant plants and OTC medicines, deliriants are largely unpopular as recreational drugs due to the severe dysphoria, uncomfortable and generally damaging cognitive and physical effects, as well as the unpleasant nature of the hallucinations.