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The duration of embryo culture can be varied, conferring different stages of embryogenesis at embryo transfer. The main stages at which embryo transfer is performed are cleavage stage (day 2 to 4 after co-incubation) or the blastocyst stage (day 5 or 6 after co-incubation). [1] Embryos which reach the day 3 cell stage can be tested for ...
Embryo transfer can be performed after various durations of embryo culture, conferring different stages in embryogenesis. The main stages at which embryo transfer is performed are cleavage stage (day 2 to 4 after co-incubation) or the blastocyst stage (day 5 or 6 after co-incubation). [10]
Gestational age: 5 weeks and 0 days until 5 weeks and 6 days old. 36–42 days from last menstruation. Embryonic age: Week nr 4. 3 weeks old. 22–28 days from fertilization. The embryo measures 4 mm (1 ⁄ 8 in) in length and begins to curve into a C shape. The heart bulges, further develops, and begins to beat in a regular rhythm.
[11]: 165 This is a horseshoe-shaped area near to the head of the embryo. By day 19, following cell signalling, two strands begin to form as tubes in this region, as a lumen develops within them. These two endocardial tubes grow and by day 21 have migrated towards each other and fused to form a single primitive heart tube, the tubular heart.
The blastocyst stage occurs between 5 and 9 days after conception. During embryonic development, after fertilization (approximately 5–6 days in the human), the cells of the morula begin to undergo cell differentiation, and the morula changes into the blastocyst by pumping fluid to grow a lumen.
The embryo becomes embedded in the endometrium in a process called implantation. In most successful pregnancies, the embryo implants 8 to 10 days after ovulation. [7] The embryo, the extra-embryonic membranes, and the placenta are collectively referred to as a conceptus, or the "products of conception".
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The incorporation of time lapse imaging tools in an incubator is a novel technology that allows images of embryo development to be captured frequently. [3] [4] This together with softwares [5] allows embryologists and clinicians to interpret the embryo development information captured and select embryos for transfer in IVF treatment.