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No screening test is wholly specific, and a high level of tumor marker can still be found in benign tumors. The only tumor marker currently used in screening is PSA (prostate-specific antigen). Diagnostics; Tumor markers alone can't be used for diagnostic purposes, due to lack of sensitivity and specificity. [5]
Tumor M2-PK is also useful to diagnose lung cancer and better than SCC and NSE tumor markers. [4] With renal cell carcinoma (RCC), the M2PK test has sensitivity of 66.7 percent for metastatic RCC and 27.5 percent for nonmetastatic RCC, but M2PK test cannot detect transitional cell carcinoma of the bladder, prostate cancer and benign prostatic ...
CA 242 is a tumor marker for sialylated Lewis carbohydrates associated with adenocarcinomas and e-selectin-mediated metastatic risk. [1] [2] [3] It is commonly tested along with CEA, CA19-9, and CA242 for detecting pancreatic cancer. [4] The specificity of CA 242 is higher than similar markers.
Cancer biomarkers have also shown utility in monitoring how well a treatment is working over time. Much research is going into this particular area, since successful biomarkers have the potential of providing significant cost reduction in patient care, as the current image-based tests such as CT and MRI for monitoring tumor status are highly ...
For example, the ColoGuard test may be used to screen people over 55 years old for colorectal cancer. [57] Cancer is a longtime-scale disease with various progression steps, molecular diagnostics tools can be used for prognosis of cancer progression. For example, the OncoType Dx test by Genomic Health can estimate risk of breast cancer.
Tumor-associated glycoprotein 72 (TAG-72) is a glycoprotein found on the surface of many cancer cells, including ovary, [1] [2] [3] breast, colon, [4] lung, and pancreatic cancers. [ 5 ] [ 6 ] It is a mucin -like molecule with a molar mass of over 1000 kDa .
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