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TNF receptor associated periodic syndrome (TRAPS [5]) is a periodic fever syndrome associated with mutations in a receptor for the molecule tumor necrosis factor (TNF) that is inheritable in an autosomal dominant manner. Individuals with TRAPS have episodic symptoms such as recurrent high fevers, rash, abdominal pain, joint/muscle aches and ...
The timing/duration of symptoms may be continuous, intermittent, and/or positional. This is dependent on the underlying cause of entrapment and the specific nerves involved. For example, pain while sitting is associated with inferior cluneal nerve entrapment, pudendal nerve entrapment, and anococcyeal nerve entrapment. [11] [12] [13]
The pain may be located close to the surface of the skin, or be deeper inside the body. Pain that is exclusively located in adjacent areas is excluded, although sometimes pain from pudendal neuralgia may be referred to those areas. [31] Pain worsened by sitting, because of increased pressure on the nerve. [17]
The pain is often initiated by sitting and walking for a longer period. [74] In 2012, one study found that 17.2% of low back pain patients met a clinical diagnosis for piriformis syndrome. [ 73 ] Piriformis syndrome does not occur in children, and is mostly seen in women of age between thirty and forty.
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Pain while sitting is a well known symptom when having ischial tuberosity [12] pain, myofascial pain syndrome, coccyx pain , failed back surgery, arachnoiditis, sciatica, piriformis syndrome, and back pain in general. An inability to sit is one of the signs of chronic low back pain. [13] Low back pain is a condition that affects a large part of ...
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Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by an abnormally large increase in heart rate upon sitting up or standing. [1] POTS is a disorder of the autonomic nervous system that can lead to a variety of symptoms, [10] including lightheadedness, brain fog, blurred vision, weakness, fatigue, headaches, heart palpitations, exercise intolerance, nausea ...