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Radial glial cells, or radial glial progenitor cells (RGPs), are bipolar-shaped progenitor cells that are responsible for producing all of the neurons in the cerebral cortex. RGPs also produce certain lineages of glia , including astrocytes and oligodendrocytes .
The progression from neural stem cell to granule cell in the SGZ can be described by tracing the following lineage of cell types: [7] [8] Radial glial cells. Radial glial cells are a subset of astrocytes, which are typically thought of as non-neuronal support cells. The radial glial cells in the SGZ have cell bodies that reside in the SGZ and ...
Oligodendrocytes are a type of glial cell, non-neuronal cells in the central nervous system.They arise during development from oligodendrocyte precursor cells (OPCs), [8] which can be identified by their expression of a number of antigens, including the ganglioside GD3, [9] [10] [11] the NG2 chondroitin sulfate proteoglycan, and the platelet-derived growth factor-alpha receptor subunit (PDGF ...
Neuroepithelial cells symmetrically divide or differentiate into progenitor cells called radial glial cells in asymmetric cell division. These can further differentiate into neurons or glial cells. Neuroepithelial cells are a class of stem cell and have the ability to self-renew.
Satellite glial cells are small cells that surround neurons in sensory, sympathetic, and parasympathetic ganglia. [19] These cells help regulate the external chemical environment. Like astrocytes, they are interconnected by gap junctions and respond to ATP by elevating the intracellular concentration of calcium ions.
Radial glial cells, also called radial glial progenitor cells, divide asymmetrically to produce a neuroblast and another radial glial cell that will re-enter the cell cycle. [5] [3] This mitosis occurs in the germinal neuroepithelium (or germinal zone), when a radial glial cell divides to produce the neuroblast. The neuroblast detaches from the ...
The subventricular zone (SVZ) is a region situated on the outside wall of each lateral ventricle of the vertebrate brain. [2] It is present in both the embryonic and adult brain. In embryonic life, the SVZ refers to a secondary proliferative zone containing neural progenitor cells, which divide to produce neurons in the process of neurogenesis. [3]
Such cells have been called hybrid brain cells because they exhibit both neuron-like and glial-like properties. Unlike traditional neurons , these cells not only transmit electrical signals but also provide supportive roles typically associated with glial cells , such as regulating the brain's extracellular environment and maintaining overall ...