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Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.
The LNCaP (Lymph Node Carcinoma of the Prostate) cell line was established from a metastatic lesion of human prostatic adenocarcinoma.The LNCaP cells grow readily in vitro (up to 8 x 10 5 cells/sq cm; doubling time, 60 hr), form clones and are highly resistant to human fibroblast interferon. [1]
The highest levels of acid phosphatase are found in metastasized prostate cancer. Diseases of the bone, such as Paget's disease or hyperparathyroidism, diseases of blood cells, such as sickle-cell disease or multiple myeloma or lysosomal storage diseases, such as Gaucher's disease, will show moderately increased levels.
The cells lining this part of the urethra differentiate into the glandular epithelium of the prostate. ... (PSA), which is an ejaculate protein produced in males, ...
A prostate-specific antigen (PSA) test is a blood test that measures the levels of a protein that is produced by prostate cells, according to City of Hope. An elevated PSA level may be a warning ...
Skene's glands produce a milk-like ultrafiltrate of blood plasma. The glands may be the source of female ejaculation , [ 3 ] [ 4 ] [ 5 ] but this has not been proven. [ 4 ] Because they and the male prostate act similarly by secreting prostate-specific antigen (PSA), which is an ejaculate protein produced in males, and prostatic acid ...