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Ketoconazole has activity against many kinds of fungi that may cause human disease, such as Candida, Histoplasma, Coccidioides, and Blastomyces (although it is not active against Aspergillus), chromomycosis and paracoccidioidomycosis. [23] [13] First made in 1977, [20] ketoconazole was the first orally-active azole antifungal medication. [23]
In July 2013, the European Medicines Agency's Committee on Medicinal Products for Human Use (CHMP) advised that oral medicines containing Ketoconazole should be suspended due to the high risk of hepatotoxicity outweighing its benefits. The advice does not affect topical ketoconazole products, and the oral use of the drug for Cushing's syndrome.
The study (which was, admittedly, very small, with just 20 people in each group) found that topical ketoconazole had a “trichogenic effect” (a fancy way of saying it produces hair) with few ...
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Miconazole is contraindicated for people who use certain drugs that are metabolized by CYP3A4, for the reasons mentioned above: [8] drugs that also prolong the QT interval because of potential problems with the heart rhythm; ergot alkaloids; statins; triazolam and oral midazolam; sulfonamides with a potential to cause hypoglycaemia (low blood ...
Here are links to possibly useful sources of information about Ketoconazole. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC
Griseofulvin is an antifungal medication used to treat a number of types of dermatophytoses (ringworm). [1] This includes fungal infections of the nails and scalp, as well as the skin when antifungal creams have not worked. [2]
Matt Bernstein, a progressive politics influencer who has over 400,000 followers on X, posted: “rip omegle, thoughts and prayers to all the 35 year old men i talked to when i was 14.” Show ...