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Fructose 1,6-bisphosphate, known in older publications as Harden-Young ester, is fructose sugar phosphorylated on carbons 1 and 6 (i.e., is a fructosephosphate). The β-D-form of this compound is common in cells. [1] Upon entering the cell, most glucose and fructose is converted to fructose 1,6-bisphosphate. [2] [3]
The molecular formula C 6 H 14 O 12 P 2 (molar mass: 340.12 g/mol) may refer to: Fructose 1,6-bisphosphate; Fructose 2,6-bisphosphate; Glucose 1,6-bisphosphate
The enzyme fructose bisphosphatase (EC 3.1.3.11; systematic name D-fructose-1,6-bisphosphate 1-phosphohydrolase) catalyses the conversion of fructose-1,6-bisphosphate to fructose 6-phosphate in gluconeogenesis and the Calvin cycle, which are both anabolic pathways: [1] [2] D-fructose 1,6-bisphosphate + H 2 O = D-fructose 6-phosphate + phosphate
Fructosephosphates are sugar phosphates based upon fructose, and are common in the biochemistry of cells. [1] Fructosephosphates play integral roles in many metabolic pathways, particularly glycolysis, gluconeogenesis and the pentose phosphate pathway. The major biologically active fructosephosphates are: Fructose 1-phosphate; Fructose 2-phosphate
They also shed light on the role of one compound as a glycolysis intermediate: fructose 1,6-bisphosphate. [13]: 151–158 The elucidation of fructose 1,6-bisphosphate was accomplished by measuring CO 2 levels when yeast juice was incubated with glucose. CO 2 production increased rapidly then slowed down. Harden and Young noted that this process ...
Fructose-2,6-bisphosphate 6-phosphatase (EC 3.1.3.54), an enzyme that catalyzes the chemical reaction beta-D-fructose 2,6-bisphosphate + H 2 O beta-D-fructofuranose 2-phosphate + phosphate; Glucose-1,6-bisphosphate synthase, a type of enzyme called a phosphotransferase and is involved in mammalian starch and sucrose metabolism
Fructose 6-phosphate (sometimes called the Neuberg ester) is a derivative of fructose, which has been phosphorylated at the 6-hydroxy group. It is one of several possible fructosephosphates. The β-D-form of this compound is very common in cells. [1] [2] The great majority of glucose is converted to fructose 6-phosphate upon entering a cell.
The aldol cleavage of fructose 1,6-bisphosphate by aldolase b demonstrates the different reaction products, dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. The generic fructose bisphosphate aldolase enzyme cleaves a 6-carbon fructose sugar into two 3-carbon products in a reverse aldol reaction.