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Neurogenic claudication (NC), also known as pseudoclaudication, is the most common symptom of lumbar spinal stenosis (LSS) and describes intermittent leg pain from impingement of the nerves emanating from the spinal cord. [1] [2] Neurogenic means that the problem originates within the nervous system.
Vascular claudication can resemble spinal stenosis, and some individuals experience unilateral or bilateral symptoms radiating down the legs rather than true claudication. [7] The first symptoms of stenosis include bouts of low back pain. After a few months or years, this may progress to claudication.
Intermittent neurogenic claudication [17] [20] [21] characterized by lower limb numbness, weakness, diffuse or radicular leg pain associated with paresthesia (bilaterally), [20] weakness and/or heaviness in buttocks radiating into lower extremities with walking or prolonged standing. [17]
Spinal or neurogenic claudication may be differentiated from arterial claudication based on activity and position. In neurogenic claudication, positional changes lead to increased stenosis (narrowing) of the spinal canal and compression of nerve roots and resultant lower extremity symptoms. Standing and extension of the spine narrows the spinal ...
Magnesium deficiency causes neurogenic inflammation in a rat model. Researchers have theorized that since substance P which appears at day five of induced magnesium deficiency, is known to stimulate in turn the production of other inflammatory cytokines including IL-1, Interleukin 6 (IL-6), and TNF-alpha (TNFα), which begin a sharp rise at day 12, substance P is a key in the path from ...
Thune said anyone who has committed a crime in the U.S. should be expelled along with the more than 1 million people already on the Biden administration’s deportation list.
William J. Hennessy Jr., a veteran sketch artist who gave Americans striking views from inside courtrooms during some of the nation’s most important legal dramas, died on Monday.
Bre Tiesi is describing her love life with Nick Cannon as "the healthiest relationship I've ever had.". The 33-year-old Selling Sunset star clarified on the Dec. 11 episode of the Wednesdays ...