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At steady state, the systemic exposure for armodafinil is 1.8 times the exposure observed after a single dose. The concentration-time profiles of the ( R )-(−)-enantiomer following a single dose of 50 mg Nuvigil or 100 mg Provigil (modafinil being a 1:1 mixture of ( R )-(−)- and ( S )-(−)- enantiomers) are nearly superimposable.
Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant and eugeroic (wakefulness promoter) medication used primarily to treat narcolepsy, [3] [8] [15] a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. [16]
Chemical structure of modafinil.. This page lists chemical compounds similar to modafinil, known as modafinil analogues and derivatives.These are structural analogues and derivatives of modafinil, a drug that affects dopamine levels in the brain in an unusual way (atypical dopamine reuptake inhibitor or DRI).
The United States Food and Drugs Administration is warning pet owners about a common medication given to pets to treat arthritis. The F.D.A. now says that the drug Librela may be associated with ...
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The parents of a 13-year-old girl who was run over by a suicidal driver in Malibu in 2010 are appealing to California Gov. Gavin Newsom to stop the felon from being released on parole.
[1] [8] [9] [10] Eugeroics, in the sense of modafinil-type wakefulness promoting agents, include modafinil itself, armodafinil , and adrafinil , among others. [ 9 ] They are medically indicated for the treatment of certain sleep disorders , including excessive daytime sleepiness (EDS) in narcolepsy or obstructive sleep apnea (OSA).
A Florida mother was arrested for saying the phrase “Delay, Deny, Depose” — in an apparent reference to the targeted UnitedHealthcare CEO killing — on a call to a health insurance company ...