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  2. Nociceptor - Wikipedia

    en.wikipedia.org/wiki/Nociceptor

    ' pain receptor ') is a sensory neuron that responds to damaging or potentially damaging stimuli by sending "possible threat" signals [1] [2] [3] to the spinal cord and the brain. The brain creates the sensation of pain to direct attention to the body part, so the threat can be mitigated; this process is called nociception .

  3. Nociception - Wikipedia

    en.wikipedia.org/wiki/Nociception

    The peduncle is not part of the lateral-spinothalamic-tract-pathway; the medulla receives the info and passes it onto the peduncle from elsewhere (see somatosensory system). The thalamus is where pain is thought to be brought into perception ; it also aids in pain suppression and modulation, acting like a bouncer , allowing certain intensities ...

  4. Gate control theory - Wikipedia

    en.wikipedia.org/wiki/Gate_control_theory

    Descending pathways also activate opioid receptor-containing parts of the spinal cord. [citation needed] Afferent pathways interfere with each other constructively, so that the brain can control the degree of pain that is perceived, based on which pain stimuli are to be ignored to pursue potential gains.

  5. Pain theories - Wikipedia

    en.wikipedia.org/wiki/Pain_theories

    Descartes' pain pathway: "Particles of heat" (A) activate a spot of skin (B) attached by a fine thread (cc) to a valve in the brain (de) where this activity opens the valve, allowing the animal spirits to flow from a cavity (F) into the muscles causing them to flinch from the stimulus, turn the head and eyes toward the affected body part, and ...

  6. Somatosensory system - Wikipedia

    en.wikipedia.org/wiki/Somatosensory_system

    The dorsal column–medial lemniscus pathway is the pathway responsible for the sending of fine touch information to the cerebral cortex of the brain. Crude touch (non-discriminating) is a sensory modality that allows the subject to sense that something has touched them, without being able to localize where they were touched (contrasting "fine ...

  7. Topographic map (neuroanatomy) - Wikipedia

    en.wikipedia.org/wiki/Topographic_map_(neuroanatomy)

    One instance would be (as already stated) in some reflexes. Reflexes usually are mediated at the level of the spinal cord through reflex arcs . In humans, mono-, oligo-, and poly-synaptic reflex arcs, propriospinal interneuron systems, and internuncial gray matter neurons collectively participate continuously to produce spinal cord reflex that ...

  8. Dorsal column–medial lemniscus pathway - Wikipedia

    en.wikipedia.org/wiki/Dorsal_column–medial...

    The dorsal column–medial lemniscus pathway (DCML) (also known as the posterior column-medial lemniscus pathway (PCML) is the major sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception (body position) from the skin and joints.

  9. Pain and pleasure - Wikipedia

    en.wikipedia.org/wiki/Pain_and_pleasure

    First, the neuroscientists, Mark Gillman and Fred Lichtigfeld demonstrated that there were two endogenous endorphin systems, one pain producing and the other pain relieving. [ 10 ] [ 11 ] [ 12 ] A short time later they showed that these two systems might also be involved in addiction, which is initially pursued, presumably for the pleasure ...