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Prazosin, sold under the brand name Minipress among others, is a medication used to treat high blood pressure, symptoms of an enlarged prostate, and nightmares related to post-traumatic stress disorder (PTSD). [6] It is an α 1 blocker. [6] It is a less preferred treatment of high blood pressure. [6] Other uses may include heart failure and ...
High doses of the α 1 blocker, prazosin, have been efficacious in treating patients with PTSD induced nightmares due to its ability to block the effects of norepinephrine. [ 27 ] Adverse effects of prazosin to treat PTSD nightmares include dizziness , first dose effect (a sudden loss of consciousness), weakness , nausea , and fatigue .
This postural hypotension usually happens shortly after the first dose is absorbed into the blood and can result in syncope (fainting). Syncope occurs in approximately 1% of patients given an initial dose of 2 mg prazosin or greater. This adverse effect is self-limiting and in most cases does not recur after the initial period of therapy or ...
High blood pressure, also called hypertension, is a vicious and smart adversary.It’s vicious because it greatly increases the odds of heart disease and stroke, some of the leading causes of ...
Prazosin was synthesized in 1974 when Constantin and Hess were trying to discover a vasodilator which had a minimal effect on cardiac activity. [7] Prazosin was a much better tolerated drug than phenoxybenzamine but the problem still remained that it lowered the blood pressure more than desired for a BPH treatment. [2] [8]
Experts call this high-functioning anxiety—when the constant hustle masks symptoms of generalized anxiety. While not an official diagnosis under the DSM-5, the classification of mental health ...
Specifically, scientists believe spicy foods are more likely to cause nightmares because they require more effort for the body to digest. They also elevate body temperature, which as stated before ...
Nightmares can be caused by extreme pressure or irritation if no other mental disorder is discovered. The death of a loved one or a stressful life event can be enough to cause a nightmare, but conditions such as post-traumatic stress disorder and other psychiatric disorders have been known to cause nightmares as well. [14]