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Therapeutic doses of radiation therapy are often given and tolerated well even at higher doses to treat discrete, well-defined anatomical structures. The same dose given over a longer period of time is less likely to cause ARS. Dose thresholds are about 50% higher for dose rates of 20 rad/h, and even higher for lower dose rates. [4]
In modern radiation therapy, 3D dose distributions are typically created in a computerized treatment planning system (TPS) based on a 3D reconstruction of a CT scan. The "volume" referred to in DVH analysis is a target of radiation treatment, a healthy organ nearby a target, or an arbitrary structure.
If only part of the body is irradiated, then only those regions are used to calculate the effective dose. The tissue weighting factors summate to 1.0, so that if an entire body is radiated with uniformly penetrating external radiation, the effective dose for the entire body is equal to the equivalent dose for the entire body.
For comparison, radiation levels inside the United States Capitol are 85 mrem/yr (0.85 mSv/yr), close to the regulatory limit, because of the uranium content of the granite structure. [14] The NRC sets the annual total effective dose of full body radiation, or total body radiation (TBR), allowed for radiation workers 5,000 mrem (5 rem). [15] [16]
Recognized effects of higher acute radiation doses are described in more detail in the article on radiation poisoning.Although the International System of Units (SI) defines the sievert (Sv) as the unit of radiation dose equivalent, chronic radiation levels and standards are still often given in units of millirems (mrem), where 1 mrem equals 1/1,000 of a rem and 1 rem equals 0.01 Sv.
The effective dose refers to the radiation risk averaged over the entire body. [4] It is the sum of the equivalent dosage of all exposed organs or tissues. [4] Equivalent dose and effective dose are measured in sieverts (Sv). [4] Dose quantities used in radiation protection
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