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The dose values are divided by the maximum dose, referred to as d max, yielding a plot in terms of percentage of the maximum dose. Dose measurements are generally made in water or "water equivalent" plastic with an ionization chamber , since water is very similar to human tissue with regard to radiation scattering and absorption.
If only part of the body is irradiated, then only those regions are used to calculate the effective dose. The tissue weighting factors summate to 1.0, so that if an entire body is radiated with uniformly penetrating external radiation, the effective dose for the entire body is equal to the equivalent dose for the entire body.
For comparison, radiation levels inside the United States Capitol are 85 mrem/yr (0.85 mSv/yr), close to the regulatory limit, because of the uranium content of the granite structure. [14] The NRC sets the annual total effective dose of full body radiation, or total body radiation (TBR), allowed for radiation workers 5,000 mrem (5 rem). [15] [16]
Therapeutic doses of radiation therapy are often given and tolerated well even at higher doses to treat discrete, well-defined anatomical structures. The same dose given over a longer period of time is less likely to cause ARS. Dose thresholds are about 50% higher for dose rates of 20 rad/h, and even higher for lower dose rates. [4]
In modern radiation therapy, 3D dose distributions are typically created in a computerized treatment planning system (TPS) based on a 3D reconstruction of a CT scan. The "volume" referred to in DVH analysis is a target of radiation treatment, a healthy organ nearby a target, or an arbitrary structure.
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