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Harrison's groove, also known as Harrison's sulcus, is a horizontal groove along the lower border of the thorax corresponding to the costal insertion of the diaphragm; it is usually caused by chronic asthma or obstructive respiratory disease. It may also appear in rickets because of defective mineralisation of the bones by calcium necessary to ...
The prominent knobs of bone at the costochondral joints of rickets patients are known as a rachitic rosary or beading of the ribs.The knobs create the appearance of large beads under the skin of the rib cage, hence the name by analogy with the beads of a Catholic Christian rosary.
Rickettsia rickettsii is a Gram-negative, intracellular, cocco-bacillus bacterium that was first discovered in 1902. [1] Having a reduced genome, the bacterium harvests nutrients from its host cell to carry out respiration, making it an organo-heterotroph.
Dictyocaulus viviparus found in the bronchi of a calf during necropsy (arrow). Parasitic bronchitis, also known as hoose, husk, or verminous bronchitis, [1] is a disease of sheep, cattle, goats, [2] and swine caused by the presence of various species of parasite, commonly known as lungworms, [3] in the bronchial tubes or in the lungs.
Rickettsia is a genus of nonmotile, gram-negative, nonspore-forming, highly pleomorphic bacteria that may occur in the forms of cocci (0.1 μm in diameter), bacilli (1–4 μm long), or threads (up to about 10 μm long).
After working as a research student from 1905 to 1907, Mellanby studied medicine at St. Thomas's Hospital in London, and in 1913 became a medical doctor. He served as a lecturer at King's College for Women in London from 1913 to 1920, during which time he was asked to investigate the cause of rickets.
No rapid laboratory tests are available to diagnose rickettsial diseases early in the course of illness, and serologic assays usually take 10–12 days to become positive. Research is indicating that swabs of eschars may be used for molecular detection of rickettsial infections.
The disease is spread by various Amblyomma ticks, and has a large economic impact on cattle production in affected areas. There are four documented manifestations of the disease, these are acute, peracute, subacute, and a mild form known as heartwater fever.