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  2. Effective population size - Wikipedia

    en.wikipedia.org/wiki/Effective_population_size

    The effective population size (N e) is the size of an idealised population that would experience the same rate of genetic drift as the real population. [1] Idealised populations are those following simple one- locus models that comply with assumptions of the neutral theory of molecular evolution .

  3. Design effect - Wikipedia

    en.wikipedia.org/wiki/Design_effect

    For example, let the design effect, for estimating the population mean based on some sampling design, be 2. If the sample size is 1,000, then the effective sample size will be 500. It means that the variance of the weighted mean based on 1,000 samples will be the same as that of a simple mean based on 500 samples obtained using a simple random ...

  4. Watterson estimator - Wikipedia

    en.wikipedia.org/wiki/Watterson_estimator

    It is a measure of the "population mutation rate" (the product of the effective population size and the neutral mutation rate) from the observed nucleotide diversity of a population. θ = 4 N e μ {\displaystyle \theta =4N_{e}\mu } , [ 3 ] where N e {\displaystyle N_{e}} is the effective population size and μ {\displaystyle \mu } is the per ...

  5. Idealised population - Wikipedia

    en.wikipedia.org/wiki/Idealised_population

    To calculate genetic diversity the authors multiply long term effective population size of the females by two, assuming sex ratio 1:1, and then multiply by mitochondrial genes substitution rate, per generation. Making several assumptions according to the sex ratio and number of juveniles, they were able to calculate that in contrast to ...

  6. Infinite alleles model - Wikipedia

    en.wikipedia.org/wiki/Infinite_alleles_model

    where u is the mutation rate, and N e is the effective population size. The effective number of alleles n maintained in a population is defined as the inverse of the homozygosity, that is = = + which is a lower bound for the actual number of alleles in the population. If the effective population is large, then a large number of alleles can be ...

  7. Prehistoric demography - Wikipedia

    en.wikipedia.org/wiki/Prehistoric_demography

    Huff et al. (2010) rejected all models with an ancient effective population size larger than 26,000. [9] For ca. 130,000 years ago, Sjödin et al. (2012) estimate an effective population size of the order of 10,000 to 30,000 individuals, and infer an actual "census population" of early Homo sapiens of roughly 100,000 to 300,000 individuals. [ 10 ]

  8. Effect size - Wikipedia

    en.wikipedia.org/wiki/Effect_size

    In statistics, an effect size is a value measuring the strength of the relationship between two variables in a population, or a sample-based estimate of that quantity. It can refer to the value of a statistic calculated from a sample of data, the value of one parameter for a hypothetical population, or to the equation that operationalizes how statistics or parameters lead to the effect size ...

  9. Effective number of codons - Wikipedia

    en.wikipedia.org/wiki/Effective_number_of_codons

    Effective number of codons (abbreviated as ENC or Nc) is a measure to study the state of codon usage biases in genes and genomes. [1] The way that ENC is computed has obvious similarities to the computation of effective population size in population genetics . [ 2 ]