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As a consequence of the biochemical reactions in which homocysteine is involved, deficiencies of vitamin B 6, folic acid (vitamin B 9), and vitamin B 12 can lead to high homocysteine levels. [2] Other possible causes of hyperhomocysteinemia include genetics, excessive methionine intake, and other diseases. [3]
Dermatophytosis as a cause of alopecia is common in cats, too, and in long-haired varieties, dermatophytic pseudomycetomas may be to blame. [7] Alopecia areata has been studied on mice in laboratories. [8] In horses, human contact with the horse and the rubbing of the saddle across the mane can cause patches of hair loss. [7]
The cat must have a supply of niacin, as cats cannot convert tryptophan into niacin. [5] However, diets high in corn and low in protein can result in skin lesions and scaly, dry, greasy skin with hair loss. [5] A deficiency of the B vitamin biotin causes hair loss around the eyes and face. [1]
It has been noted that affected cats tend to be dominating rather than submissive; some research argues that feline hyperesthesia syndrome is a form of conflict displacement, rather than just a form of general behavioural displacement, wherein the affected cat acts out thwarted territorial disputes on its own body. [9]
Perhaps the most well-known condition to cause hair loss is alopecia, which, Massick explains, “causes your own immune system to attack the hair follicles [so that] the hairs just fall out ...
Cancer in cats is the leading cause of death among cats. It is caused by uncontrolled cell growth, and affects a wide range of cell types and organs in the body. Feline cancer initially manifests as a lump or bump on any part of the body.
Cats spend 5–25% of their waking hours grooming. [3] Grooming becomes excessive when it takes precedence over other activities or no longer seems functional. [ 2 ] [ 3 ] Excessive grooming, which can lead to hair loss, skin wounds, and ulceration, can result from chronic stress or develop in cats who already exhibit nervous temperaments.
In the body, homocysteine can be recycled into methionine or converted into cysteine with the aid of vitamin B 6, B 9, and B 12. [3] High levels of homocysteine in the blood (hyperhomocysteinemia) is regarded as a marker of cardiovascular disease, likely working through atherogenesis, which can result in ischemic injury.