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In genetics, a transcription terminator is a section of nucleic acid sequence that marks the end of a gene or operon in genomic DNA during transcription.This sequence mediates transcriptional termination by providing signals in the newly synthesized transcript RNA that trigger processes which release the transcript RNA from the transcriptional complex.
Plants such as an infertile cotton strain have been made in laboratories using GURT. [1]Genetic use restriction technology (GURT), also known as terminator technology or suicide seeds, is designed to restrict access to "genetic materials and their associated phenotypic traits."
Termination signals play an important role in regulating gene expression since they mark the end of a gene transcript and determine which DNA sequences are expressed in the cell. [1] Expression levels of certain genes can be increased by inhibiting signal terminators, known as antitermination , which allows for transcription to continue beyond ...
Among these genes, however, are regulators whose products allow the next set of phage genes to be expressed. One of these types of regulator is an antitermination protein. In the absence of the antitermination protein, RNA polymerase terminates at the terminator. When the antitermination protein is present, it continues past the terminator. [1]
Here, there is no extra protein and the transcript forms its own loop structure. Intrinsic termination thus regulates the level of transcription as well, determining how many Polymerase can transcribe a gene over a given period of time, and can help prevent interactions with neighboring chromosomes. [1]
Stop codon (red dot) of the human mitochondrial DNA MT-ATP8 gene, and start codon (blue circle) of the MT-ATP6 gene. For each nucleotide triplet (square brackets), the corresponding amino acid is given (one-letter code), either in the +1 reading frame for MT-ATP8 (in red) or in the +3 frame for MT-ATP6 (in blue).
That's the route that Terminator: Dark Fate took, and while that particular plot point proved divisive, it served as a reminder that the franchise has first and foremost been Sarah's story. And ...
A nonsense mutation in one gene of an operon prevents the translation of subsequent genes in the unit. This effect is called mutational polarity. A common cause is the absence of the mRNA corresponding to the subsequent (distal) parts of the unit. Suppose that there are Rho-dependent terminators within the transcription unit, that is, before ...