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Ethylenediaminetetraacetic acid (EDTA), also called EDTA acid, is an aminopolycarboxylic acid with the formula [CH 2 N(CH 2 CO 2 H) 2] 2. This white, slightly water-soluble solid is widely used to bind to iron (Fe 2+ /Fe 3+) and calcium ions (Ca 2+), forming water-soluble complexes even at neutral pH. It is thus used to dissolve Fe- and Ca ...
Chelation therapy is an antidote for poisoning by mercury, arsenic, and lead. Chelating agents convert these metal ions into a chemically and biochemically inert form that can be excreted. Chelation using sodium calcium edetate has been approved by the U.S. Food and Drug Administration (FDA) for serious cases of lead poisoning.
Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body. [1] Chelation therapy has a long history of use in clinical toxicology [2] and remains in use for some very specific medical treatments, although it is administered under very careful medical supervision due to various inherent risks, including the mobilization of ...
EDTA chelation was found to reduce lead levels by 61 percent in the EDTA group. But cardiovascular events occurred fairly equally among the EDTA (35.6 percent) and placebo (35.7 percent) groups. ...
Ferric EDTA is the coordination complex formed from ferric ions and EDTA. ... In iron chelation therapy, deferoxamine, has been used to treat excess iron stores, ...
Although the concept and practical use of metal chelation is common, chelation of inert metals, such as platinum, has been rarely reported and the yield was extremely low. [2] To produce chelated platinum solution, tetraammonium EDTA, NTA, DTPA or HEDTA type chelating agent was mixed with platinum or platinum chemical compounds. The resulting ...
A commonly used synthetic chelator is ethylenediaminetetraacetic acid (EDTA), which may exist as a tetrasodium or disodium salt. Due to environmental and aquatic toxicity concerns regarding widespread use of EDTA in household and personal care products, alternatives such as sodium phytate/ phytic acid , tetrasodium glutamate diacetate and ...
Precursor to chelation agents, drugs, and agrochemicals [ edit ] A most prominent derivative of ethylenediamine is the chelating agent EDTA , which is derived from ethylenediamine via a Strecker synthesis involving cyanide and formaldehyde .