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Biosimulation is becoming increasingly important for drug development. [1] Since on average only 11% of all drug candidates are approved, [2] it is anticipated that biosimulation may be the tool to predict whether a candidate drug will fail in the development process e.g. in clinical trials due to adverse side effects, bad pharmacokinetics or even toxicity.
How these numerical simulations are performed, is determined through a number of "Applications", which specify whether simulations will be deterministic or stochastic, and spatial or compartmental; multiple "Applications" can also specify initial concentrations, diffusion coefficients, flow rates and a variety of modeling assumptions.
Modelling biological systems is a significant task of systems biology and mathematical biology. [a] Computational systems biology [b] [1] aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems.
A precise description of the simulation steps and other procedures used by the experiment must be provided. All simulation steps must be clearly described, including the simulation algorithms to be used, the models on which to apply each simulation, the order of the simulation steps, and the data processing to be done between the simulation steps.
Students reconstructed a chain of events in the Dr. Biology laboratory and field site, writing their own narrative for the story. Early in 2007, Ask A Biologist became one of the early content channels on iTunes U with its audio podcast of the same name. Hosted by Dr. Biology, the program was soon listed as one of five great courses by Macworld ...
PhET Interactive Simulations is part of the University of Colorado Boulder which is a member of the Association of American Universities. [10] The team changes over time and has about 16 members consisting of professors, post-doctoral students, researchers, education specialists, software engineers (sometimes contractors), educators, and administrative assistants. [11]