Search results
Results From The WOW.Com Content Network
A fluid or water deprivation test is a medical test [1] which can be used to determine whether the patient has diabetes insipidus as opposed to other causes of polydipsia (a condition of excessive thirst that causes an excessive intake of water). The patient is required, for a prolonged period, to forgo intake of water completely, to determine ...
Dipsogenic DI is a result of excessive fluid intake due to damage to the hypothalamic thirst mechanism. [1] It occurs more often in those with certain psychiatric disorders or on certain medications. [1] Gestational DI occurs only during pregnancy. [1] Diagnosis is often based on urine tests, blood tests and the fluid deprivation test. [1]
Differential diagnosis includes nephrogenic diabetes insipidus, neurogenic/central diabetes insipidus and psychogenic polydipsia. They may be differentiated by using the water deprivation test. Recently, lab assays for antidiuretic hormone are available and can aid in diagnosis.
The water deprivation test (WDT) is a commonly used test for diabetes insipidus, a two-step process involving parenteral desmopressin administration after an initial 8-hour water fast. It differentiates primary polydipsia from diabetes insipidus and central diabetes insipidus from nephrogenic diabetes insipidus .
Diagnostic tests for primary polydipsia usually involves the fluid deprivation test to exclude ADH problems. The desmopressin test is also used, in which the synthetic hormone is used as a diagnostic workup to test for inappropriate secretion of vasopressin, as seen in DI and SIADH.
Symptoms of diabetes insipidus should prompt a formal fluid deprivation test to assess the body's response to dehydration, which normally causes concentration of the urine and increasing osmolarity of the blood.
Fluid deprivation test; G. Glucose clamp technique; Glucose tolerance test; I. Insulin tolerance test; T. TRH stimulation test
The basic physiologic mechanisms of handling fluid and electrolytes by the nephron - filtration, secretion, reabsorption, and excretion - are labelled. Assessment of kidney function occurs in different ways, using the presence of symptoms and signs , as well as measurements using urine tests, blood tests, and medical imaging.