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  2. Hypereosinophilic syndrome - Wikipedia

    en.wikipedia.org/wiki/Hypereosinophilic_syndrome

    Hypereosinophilic syndrome is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. [5]

  3. Eosinophilia - Wikipedia

    en.wikipedia.org/wiki/Eosinophilia

    The hypereosinophilic syndrome is a sustained elevation in this count above 1.5 × 10 9 /L (i.e. 1,500/μL) that is also associated with evidence of eosinophil-based tissue injury. Eosinophils usually account for less than 7% of the circulating leukocytes. [ 1 ]

  4. FIP1L1 - Wikipedia

    en.wikipedia.org/wiki/FIP1L1

    The age-adjusted incidence of hypereosinophilic syndrome/chronic eosinophilic leukemia reported by the International Classification of Diseases for Oncology (Version 3) is ~0.036 per 100,000 with the mean frequency of FIP1L1-PDGFRA gene fusions occurring in ~10% of patients with hypereosinophilia as detected in developed countries. The fused ...

  5. Clonal hypereosinophilia - Wikipedia

    en.wikipedia.org/wiki/Clonal_hypereosinophilia

    Clonal hypereosinophilia, also termed primary hypereosinophilia or clonal eosinophilia, is a grouping of hematological disorders all of which are characterized by the development and growth of a pre-malignant or malignant population of eosinophils, a type of white blood cell that occupies the bone marrow, blood, and other tissues.

  6. Familial eosinophilia - Wikipedia

    en.wikipedia.org/wiki/Familial_eosinophilia

    Familial eosinophilia is a rare congenital disorder characterized by the presence of sustained elevations in blood eosinophil levels that reach ranges diagnostic of eosinophilia (i.e. 500–1500/microliter) or, far more commonly, hypereosinophilia (i.e. >1,500/microliter).

  7. Loeffler endocarditis - Wikipedia

    en.wikipedia.org/wiki/Loeffler_endocarditis

    Idiopathic hypereosinphilic syndrome and lymphocyte-variant hypereosinophilia: corticosteroids; for individuals with these hypereosinophilias that are refractory to or break through corticosteroid therapy and individuals requiring corticosteroid-sparing therapy, recommended alternative drug therapies include hydroxyurea, Pegylated interferon-α ...

  8. Glaxo Gets FDA Nod for Nucala for Hypereosinophilic Syndrome

    www.aol.com/news/glaxo-gets-fda-nod-nucala...

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  9. Eosinophilic pneumonia - Wikipedia

    en.wikipedia.org/wiki/Eosinophilic_pneumonia

    Chronic eosinophilic pneumonia was first described by Carrington [8] in 1969, and it is also known as Carrington syndrome. Prior to that, eosinophilic pneumonia was a well-described pathologic entity usually associated with medication or parasite exposures. Acute eosinophilic pneumonia was first described in 1989. [9] [10]

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