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[3] [8] The drug is available both by prescription and at lower doses over the counter. [2] [16] [4] [17] Besides for UTI prevention, methenamine is also available in a topical form to treat hyperhidrosis. [5] [6] [18] Side effects of methenamine are generally minor and include upset stomach, nausea, and headache, among others.
TMP/SMX is commonly used due to its ability to achieve high concentrations in urinary tract tissues and urine. This antibiotic combination demonstrates notable efficacy in both the treatment and prophylaxis of recurrent urinary tract infections. [12] Common adverse effects include nausea, vomiting, rash,pruritus, and photosensitivity. [26]
Urinary tract infections, bacterial prostatitis, community-acquired pneumonia, bacterial diarrhea, mycoplasmal infections, gonorrhea: Nausea (rare), irreversible damage to central nervous system (uncommon), tendinosis (rare) Inhibits the bacterial DNA gyrase or the topoisomerase IV enzyme, thereby inhibiting DNA replication and transcription ...
It is used to treat urinary tract infections, methicillin-resistant Staphylococcus aureus (MRSA) skin infections, travelers' diarrhea, respiratory tract infections, and cholera, among others. [ 2 ] [ 7 ] It is used both to treat and prevent pneumocystis pneumonia and toxoplasmosis in people with HIV/AIDS and other causes of immunosuppression. [ 2 ]
A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. [1] Lower urinary tract infections may involve the bladder ( cystitis ) or urethra ( urethritis ) while upper urinary tract infections affect the kidney ( pyelonephritis ). [ 10 ]
Fosfomycin was discovered in 1969 and approved for medical use in the United States in 1996 [globalize] [8] [10] It is on the World Health Organization's List of Essential Medicines. [11] The World Health Organization classifies fosfomycin as critically important for human medicine. [12] It is available as a generic medication. [13]