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Lab disk for protein structure analysis via small-angle X-ray scattering. The centrifugal micro-fluidic biochip or centrifugal micro-fluidic biodisk is a type of lab-on-a-chip technology, also known as lab-on-a-disc, that can be used to integrate processes such as separating, mixing, reaction and detecting molecules of nano-size in a single piece of platform, including a compact disk or DVD.
Caliper Life Sciences was founded in 1995 by Larry Bock and Drs. Michael Knapp, Michael Ramsey and Andreas Manz. as Caliper Technologies, with a focus on microfluidics technology. In 2003, the firm acquired Zymark, a company with a focus in laboratory automation and robotics, and was renamed Caliper Life Sciences.
The technology has applications in pharmaceutical research, product development, testing how different medicines, chemicals, and foods affect human health. [1] Emulate has also worked with Cedars-Sinai Medical Center on a precision medicine initiative that uses Organs-on-Chips technology in the clinical setting. [2]
Microfluidics devices also can simulate the tumor microenvironment, to help to test anticancer drugs. Microfluidic devices with 2D or 3D cell cultures can be used to analyze spheroids for different cancer systems (such as lung cancer and ovarian cancer), and are essential for multiple anti-cancer drugs and toxicity tests. This strategy can be ...
Additionally, the gut-on-a-chip allows the testing of anti-inflammatory effects of bacterial species. [31] The chip was used to model human radiation-induced injury to the intestine in vitro as it recapitulated the injuries at both cellular and tissue levels. Injuries include but not limited to: inhabitation of mucus production, promotion of ...
The company also manufactured machinery for high speed analysis of biological samples, and its GeneChip Operating Software as a system for managing Affymetrix microarray data. Affymetix's competitors in the DNA Microarray business include Illumina , GE Healthcare , Applied Biosystems , Beckman Coulter , Eppendorf Biochip Systems, and Agilent .
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