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Targeted intra-operative radiotherapy, also known as targeted IORT, is a technique of giving radiotherapy to the tissues surrounding a cancer after its surgical removal, a form of intraoperative radiation therapy. The technique was designed in 1998 at the University College London. [1]
Other radiation therapy machines which incorporate real-time MRI tracking of tumors are currently in development. MRI-guided radiation therapy enables clinicians to see a patient's internal anatomy in real-time using continual soft-tissue imaging and allows them to keep the radiation beams on target when the tumour moves during treatment. [14]
Usually therapeutic levels of radiation are delivered to the tumor bed while the area is exposed during surgery. IORT is typically a component in the multidisciplinary treatment of locally advanced and recurrent cancer, in combination with external beam radiation, surgery, and chemotherapy.
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Radiosurgery is surgery using radiation, [1] that is, the destruction of precisely selected areas of tissue using ionizing radiation rather than excision with a blade. Like other forms of radiation therapy (also called radiotherapy), it is usually used to treat cancer.
It has also been used with Stereotactic Body Radiation Therapy to assist with the initial set-up and detect intrafraction patient motion throughout treatment. [3] For stereotactic surgery , SGRT allows a frameless system to be used to monitor the surface of the patient within an open-face immobilization mask.
It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned ...
After the treatment, patients follow up with their physician for several months. The treatment team also orders additional imaging scans to evaluate whether the microwave ablation successfully destroyed the tumor. Plasma-mediated radiofrequency ablation ("coblation") Radiofrequency ablation is a treatment that uses heat to destroy multiple ...