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Globally, the most common mode of HIV transmission is via sexual contacts between people of the opposite sex; [18] however, the pattern of transmission varies among countries. As of 2017 [update] , most HIV transmission in the United States occurred among men who had sex with men (82% of new HIV diagnoses among males aged 13 and older and 70% ...
While HIV is highly virulent, transmission through sexual contact does not occur when an HIV-positive individual maintains a consistently undetectable viral load (<50 copies/ml) due to antiretroviral treatment. This concept was first proposed by the Swiss Federal Commission for AIDS/HIV in 2008 in what is known as the Swiss Statement.
HIV is commonly transmitted via unprotected sexual activity, blood transfusions, hypodermic needles, and from mother to child. Upon acquisition of the virus, the virus replicates inside and kills T helper cells , which are required for almost all adaptive immune responses .
HIV/AIDS is transmitted primarily via unprotected sexual intercourse. More than 1.1 million persons are living with HIV/AIDS in the United States, [111] and it disproportionately impacts African Americans. [112] Hepatitis B is also considered a sexually transmitted infection because it can be spread through sexual contact. [113]
While there is no cure for HIV/AIDS as of yet, prevention methods and access to medical care are major ways to know one's HIV status, become virally undetectable, and prevent transmission of HIV/AIDS. There are prevention methods to help reduce HIV rates in the United States but these methods are not equally available or accessed. [54]
HIV-2 has been found to be less pathogenic than HIV-1. [36] The mechanism of HIV-2 is not clearly defined, nor the difference from HIV-1, however the transmission rate is much lower in HIV-2 than HIV-1. Both viruses can lead to AIDS in infected individuals and both can mutate to develop drug resistance. [34]
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