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Zidovudine (ZDV), also known as azidothymidine (AZT), was the first antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. [6] It may be used to prevent mother-to-child spread during birth or after a needlestick injury or other potential exposure. [6]
Lamivudine/zidovudine, sold under the brand name Combivir among others, is a fixed-dose combination antiretroviral medication used to treat HIV/AIDS. [2] It contains two antiretroviral medications, lamivudine and zidovudine. [2] It is used together with other antiretrovirals. [2] It is taken by mouth twice a day. [2] [3]
zidovudine (AZT or ZDV) It is indicated in the treatment of AIDS/HIV-1. [2] For this purpose, the combination is very useful in pregnant women to decrease the risk of mother-to-child transmission. [6] The most common effects include headache and nausea (feeling sick). [3]
The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. [1] There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple drugs that act on different viral targets is known as highly active antiretroviral therapy ...
Commonly prescribed medications for HIV, such as sulfonamides, anticonvulsants, antibacterials, antifungals, antimycobacterials, and, most notably, antiretrovirals, have an increased incidence of adverse cutaneous drug reactions in HIV-positive individuals, and even greater escalation of incidence in people with advanced disease progression in the form of AIDS. [4]
Lamivudine may be included as part of post-exposure prevention in those who have been potentially exposed to HIV. [1] Lamivudine is taken by mouth as a liquid or tablet. [1] Common side effects include nausea, diarrhea, headaches, feeling tired, and cough. [1]
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