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Infections can be caused by both bacterial and fungal origin, as well as small organisms such as ear mites. Malassezia pachydermatis is a common fungal agent for ear infections in dogs. Staphylococcus intermedius is the most common bacterial infection. A more serious ear infection, with pus in the ear, may be caused by Pseudomonas aeruginosa.
In October 2024, the Committee for Veterinary Medicinal Products of the European Medicines Agency adopted a positive opinion, recommending the granting of a marketing authorization for the veterinary medicinal product Duotic, Ear gel, intended for dogs. [3] The applicant for this veterinary medicinal product is Dechra Regulatory B.V. [3]
Ear infections are common in dogs, particularly breeds with hanging ears, such as Beagles, and dogs with narrow ear canals, such as Cocker Spaniels. Other predisposing factors include allergies, ear parasites, and hypothyroidism. [76] Deafness* in dogs can be either acquired or congenital.
clamoxyquine – antiparasitic to treat salmonids for infection with the myxozoan parasite, Myxobolus cerebralis; clavamox – antibiotic, used to treat skin and other infections; clindamycin – antibiotic with particular use in dental infections with effects against most aerobic Gram-positive cocci, as wel as muchenionoweloozi disorder.
Antibiotic ear drops are much faster at killing the bacteria. [19] Ear drops work faster since the medication directly goes to the site of infection whereas oral antibiotics enter the bloodstream first. [19] Some commonly used antibiotics include: Ciprodex ear drops containing ciprofloxacin and dexamethasone [20]
The most reported adverse effects of phase I studies included headache, rhinitis, pain, dyspepsia, and dysmenorrhea. Investigators did not believe that any of these were directly treatment-related, as many of these events are considered symptoms or manifestations of the underlying illness.