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Neuroscientists have proposed additional models to try to explain the cause of bipolar disorder. One proposed model for bipolar disorder suggests that hypersensitivity of reward circuits consisting of frontostriatal circuits causes mania, and decreased sensitivity of these circuits causes depression. [83]
Limbic hypermetabolism is more consistent than in bipolar depression, but the overall study quality is low due to limitations associated with neuroimaging in acutely manic patients. [70] Another review reported that mania is generally associated with frontal/ventral hypoactivation, while depression is generally associated with the opposite.
Studies show that CBT, along with medication, is generally helpful for most people with bipolar disorder, except those with very severe mania. Dialectical behavioral therapy (DBT).
The trouble that researchers have had in conclusively identifying genes that cause bipolar disorder has led them to search for an epigenetic component to bipolar disorder. Epigenetics is the study of heritable phenotypes that occur without changes to the primary DNA sequence. Typically, epigenetics focuses on the expression and regulation of genes.
Bipolar disorder is a mental disorder with cyclical periods of depression and periods of elevated mood. [1] The elevated mood is significant and is known as mania, a severe elevation that can be accompanied by psychosis in some cases, or hypomania, a milder form of mania.
Soap opera star Billy Miller's mother is speaking out in the wake of her son's death at 43 years old. In a statement to Soap Opera Digest on Monday, Patricia Miller said the Daytime Emmy-winning ...