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PDE5 inhibitors are also contraindicated in patients with previous nonarteritic anterior ischaemic optic neuropathy and hereditary eye diseases. [ 1 ] Despite initial concerns of adverse cardiovascular events in patients prescribed PDE5 inhibitors, several long-term studies have established the safety of the drugs in both healthy patients and ...
Peyronie’s disease is sometimes called “curved privates disease” or simply “curvature” because ... called Phosphodiesterase-5 inhibitors, or PDE5 inhibitors, ... Prostate cancer treatments.
Vardenafil and tadalafil were discovered in 1990. These drugs came out of research programs focusing on finding PDE5 inhibitors for the treatment of cardiovascular diseases and erectile dysfunction. The two PDE5 inhibitors soon became treatments for these conditions. [22] [23]
As mentioned, Cialis can interact with other PDE5 inhibitors for ED, as well as medications prescribed to treat hypertension (high blood pressure), fungal infections, heart disease, heart failure ...
PDE5 stands for phosphodiesterase type 5, an enzyme that plays an important role in regulating blood flow to many parts of your body, including the soft tissues inside your privates.
PDE5 inhibitor drugs are effective in men regardless of why they have erectile dysfunction — including vascular disease, nerve problems, and even psychological causes. [ citation needed ] PDE5-inhibiting drugs can cause a number of side-effects , including headache , lightheadedness, dizziness , flushing, nasal congestion, and changes in vision .
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