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  2. File:Melatonin in Cancer Treatment - Current Knowledge and ...

    en.wikipedia.org/wiki/File:Melatonin_in_Cancer...

    Melatonin in Cancer Treatment: Current Knowledge and Future Opportunities: Image title: Melatonin is a pleotropic molecule with numerous biological activities. Epidemiological and experimental studies have documented that melatonin could inhibit different types of cancer in vitro and in vivo.

  3. Melatonin as a medication and supplement - Wikipedia

    en.wikipedia.org/wiki/Melatonin_as_a_medication...

    Melatonin can lower follicle-stimulating hormone levels. [52] Melatonin's effects on human reproduction remain unclear. [53] Some supplemental melatonin users report an increase in vivid dreaming. Extremely high doses of melatonin increased REM sleep time and dream activity in people both with and without narcolepsy. [54]

  4. 2-Hydroxyestrone - Wikipedia

    en.wikipedia.org/wiki/2-Hydroxyestrone

    2-Hydroxyestrone (2-OHE1), also known as estra-1,3,5(10)-trien-2,3-diol-17-one, is an endogenous, naturally occurring catechol estrogen and a major metabolite of estrone and estradiol. [ 1 ] [ 2 ] [ 3 ] It is formed irreversibly from estrone in the liver and to a lesser extent in other tissues via 2- hydroxylation mediated by cytochrome P450 ...

  5. Light effects on circadian rhythm - Wikipedia

    en.wikipedia.org/wiki/Light_effects_on_circadian...

    "In 2007, the International Agency for Research on Cancer classified shift work with circadian disruption or chronodisruption as a probable human carcinogen." [21] Exposure to light during the hours of melatonin production reduces melatonin production. Melatonin has been shown to mitigate the growth of tumors in rats.

  6. Mom diagnosed with breast cancer at 37 recalls the subtle ...

    www.aol.com/were-looking-lumps-mom-37-021957983.html

    Her cancer was HER2 positive, estrogen positive and progesterone positive, meaning that it has receptors that attract estrogen and progesterone. Bond first underwent 16 rounds of chemotherapy ...

  7. Hormonal therapy (oncology) - Wikipedia

    en.wikipedia.org/wiki/Hormonal_therapy_(oncology)

    Some members of this family, such as tamoxifen, are actually partial agonists, which can actually increase estrogen receptor signalling in some tissues, such as the endometrium. Tamoxifen is currently first-line treatment for nearly all pre-menopausal women with hormone receptor-positive breast cancer. [1]

  8. 'Soaking through my sheets': What it's like to be in ... - AOL

    www.aol.com/news/soaking-sheets-menopause-20s-30...

    People with cancer, endometriosis can experience early menopause, menopause before age 40. They feel isolated, uninformed and dismissed. 'Soaking through my sheets': What it's like to be in ...

  9. Endocrine therapy resistance in breast cancer - Wikipedia

    en.wikipedia.org/wiki/Endocrine_therapy...

    All of the forms of estrogen found in the human body are able to bind to estrogen receptors (ER) present on cells. This initiates transcription in these cells, resulting in control of gene expression. [12] Treatment strategies that work by blocking the effect of estrogen on breast cancer are referred to as endocrine (or hormone) therapies.