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Both of these factors lead to obstruction or compression of the submucosal ducts of the esophagus, leading to the formation of the pseudodiverticulae. [1] Autopsy specimens of individuals with esophageal intramucosal pseudodiverticulosis have confirmed that the flask-like openings are indeed dilated submucosal glands. [ 3 ]
The pathophysiology of cranial venous outflow obstruction involves the disruption of normal venous drainage from the brain. Cerebral veins play a crucial role in draining brain interstitial fluid (ISF), and their significance has been linked in various neurological conditions. [1] It can be caused by extrinsic or intrinsic anomalies. [7]
Dilated submucosal veins are the most prominent histologic feature of esophageal varices. The expansion of the submucosa leads to elevation of the mucosa above the surrounding tissue, which is apparent during endoscopy and is a key diagnostic feature. Evidence of recent variceal hemorrhage includes necrosis and ulceration of the mucosa.
Cerebral venous sinus thrombosis (CVST), cerebral venous and sinus thrombosis or cerebral venous thrombosis (CVT), is the presence of a blood clot in the dural venous sinuses (which drain blood from the brain), the cerebral veins, or both. Symptoms may include severe headache, visual symptoms, any of the symptoms of stroke such as weakness of ...
A vascular malformation is a type of vascular anomaly. [2] They may cause aesthetic problems as they have a growth cycle, and can continue to grow throughout life. Vascular malformations of the brain include those involving capillaries, and those involving the veins and arteries.
3D model of cerebral veins. In human anatomy, the cerebral veins are blood vessels in the cerebral circulation which drain blood from the cerebrum of the human brain. They are divisible into external (superficial cerebral veins) and internal (internal cerebral veins) groups according to the outer or inner parts of the hemispheres they drain into.
The vein of Galen can be visualized using ultrasound or Doppler. [4] A malformed Great Cerebral Vein will be noticeably enlarged. Ultrasound is a particularly useful tool for vein of Galen malformations because so many cases occur in infancy and ultrasound can make diagnoses prenatally.
Sinus pericranii is a venous anomaly where communication between the intracranial dural sinuses and dilated epicranial venous structures exists. That venous anomaly is a collection of non-muscular venous blood vessels adhering tightly to the skull's outer surface and directly communicating with intracranial venous sinuses through diploic veins.