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The most commonly used QT correction formula is the Bazett's formula, [5] named after physiologist Henry Cuthbert Bazett (1885–1950), [6] calculating the heart rate-corrected QT interval (QTcB). Bazett's formula is based on observations from a study in 1920. Bazett's formula is often given in a form that returns QTc in dimensionally suspect ...
In statistics, Sheppard's corrections are approximate corrections to estimates of moments computed from binned data. The concept is named after William Fleetwood Sheppard . Let m k {\displaystyle m_{k}} be the measured k th moment, μ ^ k {\displaystyle {\hat {\mu }}_{k}} the corresponding corrected moment, and c {\displaystyle c} the breadth ...
The q-value can be interpreted as the false discovery rate (FDR): the proportion of false positives among all positive results. Given a set of test statistics and their associated q-values, rejecting the null hypothesis for all tests whose q-value is less than or equal to some threshold ensures that the expected value of the false discovery rate is .
Prior to administration of the first dose, the corrected QT (QTc) must be determined. If the QTc is greater than 440 msec (or 500 msec in patients with ventricular conduction abnormalities), dofetilide is contraindicated. If heart rate is less than 60 bpm, the uncorrected QT interval should be used. After each subsequent dose of dofetilide, QTc ...
The effect of Yates's correction is to prevent overestimation of statistical significance for small data. This formula is chiefly used when at least one cell of the table has an expected count smaller than 5. = = The following is Yates's corrected version of Pearson's chi-squared statistics:
In statistics, expected mean squares (EMS) are the expected values of certain statistics arising in partitions of sums of squares in the analysis of variance (ANOVA). They can be used for ascertaining which statistic should appear in the denominator in an F-test for testing a null hypothesis that a particular effect is absent.
In statistics, the Q-function is the tail distribution function of the standard normal distribution. [ 1 ] [ 2 ] In other words, Q ( x ) {\displaystyle Q(x)} is the probability that a normal (Gaussian) random variable will obtain a value larger than x {\displaystyle x} standard deviations.
For example, for = 0.05 and m = 10, the Bonferroni-adjusted level is 0.005 and the Šidák-adjusted level is approximately 0.005116. One can also compute confidence intervals matching the test decision using the Šidák correction by computing each confidence interval at the ⋅ {\displaystyle \cdot } (1 − α) 1/ m % level.