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They are prescribed to treat conditions such as anxiety disorders, insomnia, and seizures. The first benzodiazepine, chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955, and was made available in 1960 by Hoffmann–La Roche, which followed with the development of diazepam (Valium) three years later, in 1963. [1]
Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic. [15] It is used to treat a range of conditions, including anxiety , seizures , alcohol withdrawal syndrome , muscle spasms , insomnia , and restless legs syndrome . [ 15 ]
The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.
It’s easier than ever for doctors to prescribe a key medicine for opioid addiction since the U.S. government lifted an obstacle last year. Researchers analyzed prescriptions filled by U.S ...
But, the complaint says, until January 2012, Pearlberg prescribed some combination of Percocet, 5 mg Valium pills, 1 mg and 2 mg Xanax pills and Roxicodone in 15 mg and 30 mg strengths.
Nationwide, prescription drugs are the costliest and commonly used heath plan benefit. Last year, BlueCross spent more than $3 billion on medications for our members. Every one of those dollars ...
Benzodiazepines are usually prescribed only short-term for the treatment of psychiatric disorders, as there is little justification for their prescribing long-term. [58] Some doctors however, disagree and believe long-term psychiatric use beyond 4 weeks is sometimes justified, although there is little data to support this viewpoint. [9]
However, single very high doses of diazepam have been found to cause lifelong immunosuppression in neonatal rats. No studies have been done to assess the immunotoxic effects of diazepam in humans; however, high prescribed doses of diazepam, in humans, have been found to be a major risk of pneumonia, based on a study of people with tetanus.