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European guidelines suggest that in children and adolescents with symptoms which are compatible with coeliac disease, the diagnosis can be made without the need for an intestinal biopsy if anti-tTG antibodies titres are very high (10 times the upper limit of normal). [9]
Because of the major implications of a diagnosis of coeliac disease, professional guidelines recommend that a positive blood test is still followed by an endoscopy/gastroscopy and biopsy. A negative serology test may still be followed by a recommendation for endoscopy and duodenal biopsy if clinical suspicion remains high. [21] [41] [93]
Autoimmune conditions related to gluten include celiac disease, dermatitis herpetiformis, and gluten ataxia.There is research showing that in people with gluten ataxia early diagnosis and treatment with a gluten-free diet can improve ataxia and prevent its progression. [9]
Children with celiac disease often present with symptoms like abdominal distension or bloating, as well as failure to thrive, anemia and diarrhea. Because these symptoms are vague and can be related to many other conditions or food allergies, celiac disease can be difficult to diagnose unless there is a family history to help as a cue.
"Guideline for the Diagnosis and Treatment of Celiac Disease in Children: Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition". Journal of Pediatric Gastroenterology and Nutrition. 40 (1): 1– 19. doi: 10.1097/00005176-200501000-00001. PMID 15625418. S2CID 14805217.
Blood testing and stool testing is often also suggested, Chey adds, in order to rule out other causes for symptoms such as inflammation associated with conditions such as celiac disease or chronic ...
Enteropathy-associated T-cell lymphoma (EATL), previously termed enteropathy-associated T-cell lymphoma, type I and at one time termed enteropathy-type T-cell lymphoma (ETTL), is a complication of coeliac disease in which a malignant T-cell lymphoma develops in areas of the small intestine affected by the disease's intense inflammation. [1]
Upper respiratory tract symptoms: Emerging evidence suggests that eating 100 grams of barley per day, instead of white rice, may help ease upper respiratory tract symptoms like congestion and ...