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An upper respiratory tract infection (URTI) is an illness caused by an acute infection, which involves the upper respiratory tract, including the nose, sinuses, pharynx, larynx or trachea. [3] [4] This commonly includes nasal obstruction, sore throat, tonsillitis, pharyngitis, laryngitis, sinusitis, otitis media, and the common cold.
The lower respiratory tract consists of the trachea (windpipe), bronchial tubes, bronchioles, and the lungs. [6] Lower respiratory tract infections (LRIs) are generally more severe than upper respiratory infections. LRIs are the leading cause of death among all infectious diseases. [7] The two most common LRIs are bronchitis and pneumonia. [8]
Pharyngitis is a type of upper respiratory tract infection. [7] Most cases are caused by a viral infection. [2] Strep throat, a bacterial infection, is the cause in about 25% of children and 10% of adults. [2] Uncommon causes include other bacteria such as gonococcus, fungi, irritants such as smoke, allergies, and gastroesophageal reflux disease.
The common cold is an infection of the upper respiratory tract which can be caused by many different viruses. The most commonly implicated is a rhinovirus (30–80%), a type of picornavirus with 99 known serotypes. [33]
Pneumonia frequently starts as an upper respiratory tract infection that moves into the lower respiratory tract. [55] It is a type of pneumonitis (lung inflammation). [56] The normal flora of the upper airway give protection by competing with pathogens for nutrients.
The most common upper respiratory tract infection is the common cold. However, infections of specific organs of the upper respiratory tract such as sinusitis, tonsillitis, otitis media, pharyngitis and laryngitis are also considered upper respiratory tract infections. [citation needed]