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The French Louis Pasteur (1822–1895) and German Robert Koch (1843–1910) are the two greatest figures in medical microbiology and in establishing acceptance of the germ theory of disease (germ theory). [1] In 1882, fueled by national rivalry and a language barrier, the tension between Pasteur and the younger Koch erupted into an acute ...
Louis Pasteur's contemporary Robert Koch devoted much of his scientific study to discovering certain pathogens and connecting them to specific diseases. These scientists were often in competition with one another and so the Koch-Pasteur rivalry is a well-known part of germ theory's history.
Heinrich Hermann Robert Koch (/ k ɒ x / KOKH; [1] [2] German: [ˈʁoːbɛʁt ˈkɔx] ⓘ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist.As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera and anthrax, he is regarded as one of the main founders of modern bacteriology.
Koch's postulates (/ k ɒ x / KOKH) [2] are four criteria designed to establish a causal relationship between a microbe and a disease. The postulates were formulated by Robert Koch and Friedrich Loeffler in 1884, based on earlier concepts described by Jakob Henle , and the statements were refined and published by Koch in 1890. [ 3 ]
1882–1889: Koch–Pasteur rivalry: Louis Pasteur, Robert Koch. 1899–1902 discovery of the life cycle of malarial parasite: Giovanni Battista Grassi, Ronald Ross [14] [15] [16] 1953–1962 discovery of the DNA structure: Francis Crick, James D. Watson, Rosalind Franklin, Erwin Chargaff, Oswald Avery [17] [18] [19]
Despite his other successes, Louis Pasteur (1822–1895) was unable to find a causative agent for rabies and speculated about a pathogen too small to be detected using a microscope. [1] In 1884, the French microbiologist Charles Chamberland (1851–1931) invented a filter – known today as the Chamberland filter – that had pores smaller than ...
Nothing grew in the broths in the course of Pasteur's experiment. This meant that the living organisms that grew in such broths came from outside, as spores on dust, rather than spontaneously generated within the broth. Thus, Pasteur refuted the theory of spontaneous generation and supported the germ theory of disease. [17]
Louis Pasteur FRS Photograph by Nadar, 1895 Born (1822-12-27) 27 December 1822 Dole, France Died 28 September 1895 (1895-09-28) (aged 72) Marnes-la-Coquette, France Education École normale supérieure University of Paris Known for Anthrax vaccine Cholera vaccine Rabies vaccine Chirality Dextran Fermentation theory Galactose Germ theory of disease Kinetic resolution Koch–Pasteur rivalry ...