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  2. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes, or symptomatic heart failure.

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]

  4. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

  5. The financial hit of a missed appointment varies by specialty, depending on the staff, resources and equipment that were assigned to the patient but were not utilized because of the no-show.

  6. ELIQUIS® (apixaban) Approved In Japan For The ... - AOL

    www.aol.com/news/2012-12-26-eliquis-apixaban...

    ELIQUIS ® (apixaban) ... 24/7 Help. For premium support please call: 800-290-4726 more ways to reach us. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 more ways to reach us.

  7. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.

  8. When Is the Best Time to Take Metformin? - AOL

    www.aol.com/best-time-metformin-141700387.html

    The same advice goes here, too: If you take metformin twice or three times a day, aim to take it at the same times each day. ... But if it’s close to the time of your next dose, skip the missed ...

  9. Deep vein thrombosis - Wikipedia

    en.wikipedia.org/wiki/Deep_vein_thrombosis

    Rivaroxaban and apixaban are the typical first-line medicines, and they are sufficient when taken orally. [19] Rivaroxaban is taken once daily, and apixaban is taken twice daily. [ 5 ] Warfarin, dabigatran, and edoxaban require the use of a parenteral anticoagulant to initiate oral anticoagulant therapy.