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The Habsburg Philip II of Spain and his wife, the Tudor Mary I of England.Mary and Philip were first cousins once removed. The wedding of Nicholas II of Russia and Alix of Hesse (whose name was changed to Alexandra Feodorovna in the process), second cousins through their shared great-grandparents Louis II, Grand Duke of Hesse, and Wilhelmine of Baden
The unofficial leader of these groups was Otto von Habsburg, who campaigned against the Nazis and for a free Central Europe in France and the United States. Most of the resistance fighters, such as Heinrich Maier , who successfully passed on production sites and plans for V-2 rockets , Tiger tanks and aircraft to the Allies , were executed.
The House of Habsburg gives a well-documented example of pedigree collapse. In the case of Charles II, the last Habsburg King of Spain, there were three uncle-niece marriages among the seven unions of his immediate ancestry (i.e. parents, grandparents and great-grandparents). His father and two of his great-grandfathers married their nieces.
Maria Antonia had the highest coefficient of inbreeding in the House of Habsburg, 0.3053: [6] her father was her mother's maternal uncle and paternal first cousin once removed, and her maternal grandparents were also uncle and niece. Her coefficient was higher than that of a child born to a parent and offspring, or brother and sister.
The Habsburg monarchy, [i] also known as Habsburg Empire, or Habsburg Realm [j] (/ ˈ h æ p s b ɜːr ɡ /), was the collection of empires, kingdoms, duchies, counties and other polities that were ruled by the House of Habsburg. From the 18th century it is also referred to as the Austrian monarchy (Latin: Monarchia Austriaca) or the Danubian ...
Inbreeding is also used to reveal deleterious recessive alleles, which can then be eliminated through assortative breeding or through culling. In plant breeding, inbred lines are used as stocks for the creation of hybrid lines to make use of the effects of heterosis. Inbreeding in plants also occurs naturally in the form of self-pollination.
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The family intermarried multiple times, securing power and influence across a European empire for 200 years - but it came with an unusual side-effect.