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A moderate degree of iron-deficiency anemia affects approximately 610 million people worldwide or 8.8% of the population. [75] It is slightly more common in females (9.9%) than males (7.8%). [75] Up to 15% of children ages 1–3 years have iron deficiency anemia. [48] Mild iron deficiency anemia affects another 375 million. [75]
Red blood cells normally survive an average of about 120 days, becoming damaged (their oxygen-carrying capacity becomes compromised) as they age.
If left untreated, acute iron poisoning can lead to multi-organ failure resulting in permanent organ damage or death. [1] Iron is available over the counter as a single entity supplement in an iron salt form or in combination with vitamin supplements and is commonly used in the treatment of anemias.
Iron-deficiency anemia is the most common type of anemia overall and it has many causes. RBCs often appear hypochromic (paler than usual) and microcytic (smaller than usual) when viewed with a microscope. Iron-deficiency anemia is due to insufficient dietary intake or absorption of iron to meet the body's needs. Infants, toddlers, and pregnant ...
Iron deficiency, or sideropenia, is the state in which a body lacks enough iron to supply its needs. Iron is present in all cells in the human body and has several vital functions, such as carrying oxygen to the tissues from the lungs as a key component of the hemoglobin protein, acting as a transport medium for electrons within the cells in the form of cytochromes, and facilitating oxygen ...
Iron pills are usually prescribed to treat iron deficiency anemia. “Iron is essential for making hemoglobin, the protein in red blood cells responsible for carrying oxygen throughout the body ...
These women did have anemia, but it was not attributed to low levels of iron. The conclusion of the study stated "We do not recommend the use of the fish-shaped iron ingot in Cambodia or in countries where the prevalence of iron deficiency is low and genetic hemoglobin disorders are high".
The body regulates iron levels by regulating each of these steps. For instance, enterocytes synthesize more Dcytb, DMT1 and ferroportin in response to iron deficiency anemia. [13] Iron absorption from diet is enhanced in the presence of vitamin C and diminished by excess calcium, zinc, or manganese. [14]