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This is a list of adverse effects of the antidepressant trazodone, sorted by frequency of occurrence. [1] [2] [3] Very common.
Trazodone lacks any affinity for the muscarinic acetylcholine receptors, so does not produce anticholinergic side effects. mCPP, a non-selective serotonin receptor modulator and serotonin releasing agent , is an active metabolite of trazodone and has been suggested to possibly play a role in its therapeutic benefits.
Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal.
Note that trazodone is not a tetracyclic chemical (four joined rings), rather it has several separate cyclic structures. To quote 'Trazodone is a triazolopyridine derivative, chemically and structurally unrelated to tricyclic and tetracyclic antidepressants' Gribskov 11:54, 14 October 2006 (UTC)
WebMD is an American corporation which publishes online news and information about human health and well-being. [4] The WebMD website also includes information about drugs and is an important healthcare information website and the most popular consumer-oriented health site. [5] WebMD was started in 1998 by internet entrepreneur Jeff Arnold. [6]
WebMD’s parent company goes nuclear on return to office in an uncanny leaked video: ‘We need you ready and present, and we need it now’ Jane Thier January 11, 2024 at 12:50 PM
Although usually reversible, these sexual side-effects can, in rare cases, continue after the drug has been completely withdrawn. [ 158 ] [ 159 ] In a study of 1,022 outpatients, overall sexual dysfunction with all antidepressants averaged 59.1% [ 160 ] with SSRI values between 57% and 73%, mirtazapine 24%, nefazodone 8%, amineptine 7%, and ...
Antidepressants could increase the risk of suicidal thoughts and behavior in people with depression under the age of 25. In 2004, the U.S. Food and Drug Administration along with the Neuro-Psychopharmacologic Advisory Committee and the Anti-Infective Drugs Advisory Committee, concluded that there was a causal link between newer antidepressants and pediatric suicidality. [7]