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Proctosigmoiditis and left-sided colitis involves the lower colon, from the rectum up the left side of the patient. Patients often respond to topical agents alone, such as Mesalazine, or hydrocortisone enemas. Again, the Mesalazine is preferred for maintenance therapy. Initially a 4 g Mesalazine enema (Rowasa) is given nightly.
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The mean age of those experiencing ischemic colitis after a glycerin enema was 70 years, and the mean time to ischemic colitis onset was 5.5 hours after enema administration. [4] Chemical colitis may trigger a flare of ulcerative colitis or Crohn's colitis. [citation needed] Treatment is usually with supportive care until the colitis resolves.
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